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Summary : The unique force of Jane Austen's novels lies in the interplay of character. Nothing much happens, on the surface; but, as in life, minor shifts and changes evoke enormous consequences in the lives of individuals. In this stimulating book, Ivor Morris anatomises one of her best-loved characters: 'conceited, pompous, narrow-minded, silly' Mr Collins.
Summary : This volume contains a selection of papers presented at the second workshop on Evaluation and Planning held at Centre International de Hautes Etudes Agronomiques Mediterraneennes (CIHEAM) in Valenzano (Bari) in November 1993. The workshop was financially and otherwise supported by the School of Engineering, Bari Polytechnic; the School of Agriculture, University of Bari; and CIHEAM. The publication of this book was made possible by to the efforts of the contributing authors. Several other persons have provided invaluable support for the workshop or the preparation of this volume. One of these is Patsy Healey for her fascinating challenge to Andreas Faludi's most recent arguments about rational planning theory. Another is John Friedmann whose lecture at the workshop presented world future scenarios depicting interaction between economic growth, social justice and ecological balance. Angela Barbanente provided marvelous support in organizing the workshop and editorial advice in the preparation of this volume. Jeremy Franks carefully improved the English and the clarity of all the papers. Carmelo Torre made a final editing of texts and images. We owe thanks to Maurizio Raeli for providing all the support services during the workshop and Claudia Baublys for her excellent help with various administrative issues with regard to the workshop and publication of this book. This book is dedicated to the memory of Professor Giovanni Grittani, Professor of Land Economics, University of Bari.
Summary : The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics reasearch. This thematic volume of Advances in Genetics looks at Socio-Genetics. * Includes methods for testing with ethical, legal, and social implications * Critically analyzes future prospects
Summary : In complex systems, such as our body or a plant, the host is living together with thousands of microbes, which support the entire system in function and health. The stability of a microbiome is influenced by environmental changes, introduction of microbes and microbial communities, or other factors. As learned in the past, microbial diversity is the key and low-diverse microbiomes often mirror out-of-control situations or disease. It is now our task to understand the molecular principles behind the complex interaction of microbes in, on and around us in order to optimize and control the function of the microbial community – by changing the environment or the addition of the right microorganisms. This Research Topic focuses on studies (including e.g. original research, perspectives, mini reviews, and opinion papers) that investigate and discuss: 1) The role of the microbiome for the host/environmental system 2) The exchange and change of microbes and microbial communities (interplay) 3) The influence of external factors toward the stability of a microbiome 4) Methods, possibilities and approaches to change and control a system’s microbiome (e.g. in human or plant disease) 5) Experimental systems and approaches in microbiome research. The articles span the areas: human health and disease, animal and plant microbiomes, microbial interplay and control, methodology and the built environment microbiome.
Summary : This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.
Summary : The lives of Catullus and Horace overlap by a dozen years in the first century BC. Yet, though they are the undisputed masters of the lyric voice in Roman poetry, Horace directly mentions his great predecessor, Catullus, only once, and this reference has often been taken as mocking. In fact, Horace's allusion, far from disparaging Catullus, pays him a discreet compliment by suggesting the challenge that his accomplishment presented to his successors, including Horace himself. In Poetic Interplay, the first book-length study of Catullus's influence on Horace, Michael Putnam shows that the earlier poet was probably the single most important source of inspiration for Horace's Odes, the later author's magnum opus. Except in some half-dozen poems, Catullus is not, technically, writing lyric because his favored meters do not fall into that category. Nonetheless, however disparate their preferred genres and their stylistic usage, Horace found in the poetry of Catullus, whatever its mode of presentation, a constant stimulus for his imagination. And, despite the differences between the two poets, Putnam's close readings reveal that many of Horace's poems echo Catullus verbally, thematically, or both. By illustrating how Horace often found his own voice even as he acknowledged Catullus's genius, Putnam guides us to a deeper appreciation of the earlier poet as well.
Summary : Philosophy as Interplay and Dialogue is an original and stimulating collection of essays. It covers conceptual and critical works relevant to current theoretical developments and debates. An international group of philosophers of education come together each summer on a Greek island. This book is the product of their diligent philosophical analysis and extended dialogues. To deploy their arguments, the authors draw on classical thinkers and contemporary prominent theorists, such as Badiou and Malabou, with fresh and critical perspectives. This book thus makes an original contribution to the field. (Series: Studies on Education, Vol. 5) [Subject: Philosophy of Education]
Summary : This edited volume of case studies presents a selective history of French music and culture, but one with a dynamic difference. Eschewing a traditional chronological account, the book explores the nature of relationships between one main period, broadly the 'long' modernist era between 1860–1960, and its own historical ‘others’, referencing topics from the Romantic, classical, baroque, renaissance and medieval periods. It probes the emergent interplay, intertextualities and scope for reinterpretation across time and place. Notions of cultural meaning are paramount, especially those pertaining to French identity, national and individual. While founded on historical musicology, the approach benefits from interdisciplinary association with philosophy, political history, literature, fine art, film studies and criticism. Attention is paid to French composers’ celebrations and remakings of their predecessors. Editions of and writings about earlier music are examined, together with the cultural reception of performances of past repertoire. Organized into two parts, each of the eleven chapters characterizes a specific cultural network or temporal interplay, which may result in synthesis, disjunction, or historical misreading. The interwar years and those surrounding the Second World War prove particularly rich sources of enquiry. This volume aims to attract a wide readership of musicologists and musicians, as well as cultural historians, other humanities scholars and concert-goers.
Summary : Various cellular processes underlying plant development and response to environmental cues rely on a dynamic interplay between membranes and the cytoskeleton, e.g. vesicle and organelle trafficking, endocytosis, exocytosis, and signal transduction. In recent years, significant progress in the understanding of such interplay has been achieved and several critical links between membranes and the cytoskeleton have been characterized. As an example, recent work has clarified how auxin promotes the reorganization of cortical actin filaments by the activation of Rho GTPase pathways, and how such reorganization in turn locally modifies endocytosis and/or exocytosis and directs asymmetric distribution of PIN family of auxin transporters. Another recent achievement is the characterization of the Rho- and microtubule-driven mechanism by which the cell wall architecture is established. In particular, the elegant work by Oda and Fukuda (Science 337 p.1333, 2012) provides evidence that secondary wall patterning in xylem vessel primarily relies on two processes: a local activation of the plant Rho GTPase ROP11 and a mutual, MIDD1-mediated, inhibitory interaction between active ROP domains and cortical microtubules. Additional examples include recent genetic evidence that microtubule and actin filament interacting/regulatory proteins, such as MAP65-1 and capping protein, function as transducers of membrane lipid signaling into changes in cytoskeleton dynamics and organization. This Research Topic aims at collecting a comprehensive set of articles dealing with cellular processes involving membrane-cytoskeleton interactions. Its scope extends beyond the specific fields defined by the above examples and includes intracellular trafficking, host-pathogen interactions, response to biotic and abiotic stresses and hormonal regulation of growth. We hope that this Research Topic will also highlight critical questions that need to be addressed in the future. We welcomed Original Research Articles, Technical/Methodological Advances (e.g. analysis of cytoskeleton dynamics close to membranes), Reviews and Mini Reviews that can expand our understanding of how and why membranes and the cytoskeleton interact.
Summary : The poet-herdsmen of Vergil's 'Eclogues' employ differing strategies for coping with acute loss, whether external or internal. The interplay of ideas latent in several of their songs is typically framed in terms of Epicurean concepts.
Summary : Covers recent developments in galaxy evolution, a valuable resource for those working in extragalactic astronomy.
Summary : Are international tribunals heading towards greater sovereignty or towards greater liberalisation of property rights? Can we glean specific deductions from prevailing cases outside the expropriation arena? How can we justifiably extrapolate principles from international investment arbitration before modifying and applying these lessons to international human rights, the World Trade Organization regime and other dispute settlement systems? What, if any, degree of deference attends the assessment of various claims undertaken by international tribunals? Does this depend on high commerce, force majeure, military or paramilitary control, urgent nuclear and environmental considerations, transboundary harms, political instability, fraud and deception or other special circumstances? Where do textually strict treaty interpretations end and the general principles of international law take over? Can autonomous treaty interpretation by international tribunals be reconciled with the host State’s prerogative of defining its own protected public interests? Where is the tipping point, too frequently fraught with the potential to deprive States of the incentive to stay within the applicable international compact? These issues must be comparatively addressed. Contemporary international law developments and dislocations are occurring at a break-neck pace. We pause and contemplate the implications. Riddhi Dasgupta analyses the standards of Expropriation, Exhaustion of Local Remedies, Continuous Nationality, Non-Discrimination (National Treatment, Most Favoured Nation and Domestic Discrimination), Fair and Equitable Treatment, Minimum Standard of Treatment, and Compensation across international dispute settlement. The foundational and evolving concept of consent is required to justify all public international law, from genesis onwards. The potency of expropriation-based claims will continue to expand, and the comparative lessons drawn from various international law regimes will interplay to stirring effect. Writing accessibly, Dasgupta proposes various legal strategies going forward and makes analytical prognostications about this area of international law. Dasgupta presents influential interview and anecdotal results as well as statistics concerning the growing flow of investments in targeted jurisdictions and sectors. For the international lawyer’s benefit, the final chapter condenses the book’s tactical scenario-planning and advice. Institutional dialogues among tribunals as well as tribunal dialogues with politicians, investors, NGOs, and of course citizens (the ultimate boson) will assume absolutely indispensable significance. This will be the true tipping-point in the eye of the storm. Legitimacy, transparency, justice, efficiency and economy, candour, party autonomy, coherence, incentives, and the tense clash of interests reappear as the constant motifs in this important but relatively unknown saga. Studiedly neutral in its orientation, this book strives to promote constructive solutions as well as public awareness.