Hematopoietic Stem Cell Transplantation In Clinical Practice

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Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Jennifer Treleaven,Austin John Barrett
  • Publisher :
  • Release Date :2009
  • Total pages :555
  • ISBN : 9780443101472
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Summary : A guide to the practice of stem cell transplantation, its status in the treatment of various disorders and the problems that arise after transplantation, aimed at the whole transplant team. An up to date guide to best practice in the use of stem cell transplantation, covering current status in the treatment of malignant and non-malignant conditions, practical aspects and problems such as infection and graft versus host disease. Has a practical, accessible approach with free use of algorithms, list tables. Aimed at the whole transplant team - this is an interdisciplinary field. International contributor team with editors in the UK and USA. Illustrated in colour throughout.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Susan Ezzone
  • Publisher :
  • Release Date :2012-10
  • Total pages :326
  • ISBN : 9781935864196
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Summary : Since the publication of the first edition of this book in 2004, the specialty of hematopoietic stem cell transplantation (HSCT) has continued to progress as a treatment option for many diseases. Indications for the use of autologous, syngeneic, and allogeneic transplantation continue to expand. The second edition of Hematopoietic Stem Cell Transplantation: A Manual for Nursing Practice presents the most up-to-date information regarding the use of HSCT. Chapter topics include an overview of hematopoiesis and immunology, basic concepts of transplantation, stem cell collection, course of transplant treatment and acute complications, acute and chronic graft-versus-host disease, various complications from gastrointestinal to neurologic, relapse, long-term care and survivorship, ethics, and much more.

Clinical Bone Marrow and Blood Stem Cell Transplantation

Clinical Bone Marrow and Blood Stem Cell Transplantation
  • Author : Kerry Atkinson,Richard Champlin,Jerome Ritz,Willem E. Fibbe,Per Ljungman,Malcom K. Brenner
  • Publisher :
  • Release Date :2004
  • Total pages :1968
  • ISBN : 9780521829120
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Summary : Drs Richard Champlin, Jerome Ritz, Willem Fibbe, Per Ljungman, and Malcom K. Brenner join Kerry Atkinson as editors of this definitive reference on the clinical practice and underlying science of hematopoietic stem cell transplantation. This third edition text is significantly revised and updated with 124 chapters balancing scientific explanations with practical information on patient care for all aspects of autologous, syngeneic, and allogeneic transplantation. This edition includes 18 new chapters on significant topics such as plasticity of stem cells, embryonic stem cells, and nonmyeloablative conditioning regimens. Thoroughly referenced through 2003, the chapters are divided into 15 sections, including biological background and practical procedures, clinical results, transplant-related and organ-specific complications, laboratory aspects, and developing areas, with a final 'breaking news' chapter from this rapidly evolving field. Over 170 internationally-recognized experts contributed to this authoritative and practical text that is an essential resource for hematologists, oncologists, and transplant specialists.

Stem Cells in Clinical Practice and Tissue Engineering

Stem Cells in Clinical Practice and Tissue Engineering
  • Author : Rakesh Sharma
  • Publisher :
  • Release Date :2018-05-02
  • Total pages :352
  • ISBN : 1789230101
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Summary : Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

Tumorablative Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of High-Risk and Refractory Leukemia - New Concepts and Clinical Practice

Tumorablative Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of High-Risk and Refractory Leukemia - New Concepts and Clinical Practice
  • Author : Wan-ming Da Yong
  • Publisher :
  • Release Date :2013
  • Total pages :329
  • ISBN :
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Summary : Tumorablative Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of High-Risk and Refractory Leukemia - New Concepts and Clinical Practice.

The European Blood and Marrow Transplantation Textbook for Nurses

The European Blood and Marrow Transplantation Textbook for Nurses
  • Author : Michelle Kenyon,Aleksandra Babic
  • Publisher :
  • Release Date :2018-03-14
  • Total pages :311
  • ISBN : 3319500260
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Summary : This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Blood and Marrow Stem Cell Transplantation

Blood and Marrow Stem Cell Transplantation
  • Author : Susan Ezzone,Kim Schmit-Pokorny
  • Publisher :
  • Release Date :2007
  • Total pages :521
  • ISBN : 9780763747190
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Summary : Blood and Marrow Stem Cell Transplantation, Third Edition serves as a convenient reference for oncology nurses caring for blood and marrow stem cell transplantation recipients. The Third Edition has been updated and revised to reflect the most current research related to the past, present, and future of blood and marrow stem cell transplants. This resource covers everything from preparing for transplantation surgery, to recovery-related issues and delayed outcomes. Basic background information on transplantation procedures and processes are provided, along with in-depth coverage of pulmonary, cardiac, renal and hepatic, neurologic, and hematologic effects. A chapter devoted to controversial ethical issues is also provided. Blood and Marrow Stem Cell Transplantation, Third Edition presents complete, up-to-date coverage of the transplantation process from beginning to end.

Allogeneic Stem Cell Transplantation

Allogeneic Stem Cell Transplantation
  • Author : Hillard M. Lazarus,Mary J. Laughlin
  • Publisher :
  • Release Date :2010-03-02
  • Total pages :881
  • ISBN : 9781597454780
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Summary : Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

The EBMT Handbook

The EBMT Handbook
  • Author : Enric Carreras,Carlo Dufour,Mohamad Mohty,Nicolaus Kröger
  • Publisher :
  • Release Date :2018-12-12
  • Total pages :702
  • ISBN : 3030022781
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Summary : This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers’ knowledge and practice skills.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation
  • Author : Gerard Socie,Robert Zeiser,Bruce R. Blazar
  • Publisher :
  • Release Date :2018-11-22
  • Total pages :430
  • ISBN : 0128134399
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Summary : Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Kim Schmit-Pokorny,Seth Eisenberg
  • Publisher :
  • Release Date :2020
  • Total pages :329
  • ISBN : 9781635930412
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Summary : "Hematopoietic stem cell transplantation (HSCT) has evolved from primary use in hematologic malignancies and nonmalignant disease and solid tumors into a treatment option for many other diseases, and indications for HSCT continue to expand. The new edition of this manual provides comprehensive information on the ever-evolving specialty of HSCT, providing nurses and other practitioners with in-depth information on the entire HSCT process, from stem cell mobilization, collection, and infusion to potential complications and long-term effects. It also includes chapters on current research, emerging therapies, ethics, HSCT program development, and professional practice issues"--

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Anthony D. Ho,Rainer Haas,Richard E. Champlin
  • Publisher :
  • Release Date :2000-07-25
  • Total pages :624
  • ISBN : 9780824702731
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Summary : This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life. Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation summarizes current understanding and development of clinical allogeneic HSC transplantation discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors details detection of bone marrow contamination by tumor cells and removal procedures focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors explores the effects of growth factor administration and leukapheresis on PB stem cell donors shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells employs automated fluorescence image cytometry to study early HSC behavior following seeding Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study, Hematopoietic Stem Cell Transplantation is a blue-chip reference for hematologists, hematopathologists, oncologists, cytotherapists, transplantation immunologists, and molecular biologists.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Anthony D. Ho,Rainer Haas,Richard E. Champlin
  • Publisher :
  • Release Date :2000-07-25
  • Total pages :624
  • ISBN : 9780824741815
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Summary : This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life. Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation summarizes current understanding and development of clinical allogeneic HSC transplantation discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors details detection of bone marrow contamination by tumor cells and removal procedures focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors explores the effects of growth factor administration and leukapheresis on PB stem cell donors shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells employs automated fluorescence image cytometry to study early HSC behavior following seeding Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study, Hematopoietic Stem Cell Transplantation is a blue-chip reference for hematologists, hematopathologists, oncologists, cytotherapists, transplantation immunologists, and molecular biologists.

Establishing a Hematopoietic Stem Cell Transplantation Unit

Establishing a Hematopoietic Stem Cell Transplantation Unit
  • Author : Éliane Gluckman,Dietger Niederwieser,Mahmoud Aljurf
  • Publisher :
  • Release Date :2017-11-17
  • Total pages :306
  • ISBN : 3319593587
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Summary : This text aims to provide simplified practical guidelines to start a hematopoietic stem cell transplantation unit which could be implemented in most centers and countries worldwide. The book also provides guidelines for existing transplantation units to upgrade their practice and implement new policies and procedures, in addition to developing therapies according to latest international standards and regulations. The book covers a wide range of practical implementation tools including HSCT program team structure, building inpatient and outpatient HSCT units, requisite laboratory support for transplantation program, practical aspects of stem cell collection and processing, HSCT program quality management, education and training, and data management. The book also addresses cost effectiveness and recommendations for establishing transplantation program in countries with limited resources. Written by group of internationally established experts in their corresponding hematopoietic stem cell transplantation fields, with contributions from many leaders of hematopoietic stem cell transplantation organizations, Establishing a Hematopoietic Stem Cell Transplantation Unit: A Practical Guide is an essential, practical resource for all members of the multidisciplinary hematopoietic stem cell transplantation team.

Pediatric Hematopoietic Stem Cell Transplantation for Pharmacists

Pediatric Hematopoietic Stem Cell Transplantation for Pharmacists
  • Author : Carolina Witchmichen Penteado Schmidt
  • Publisher :
  • Release Date :2020-06-02
  • Total pages :123
  • ISBN : 3030434915
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Summary : This unique book is the first on pediatric hematopoietic stem cell transplantation that is especially intended for pharmacists – in recognition of the fact that Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice, yet pharmacists who work in pediatric stem cell transplantation do not have a book addressing their specific needs. This pioneering book will likely become the new gold standard for practice, addressing subjects such as stem cells and their differentiation mechanisms; aspects of embryonic and non-embryonic stem cells; stem cell transplantation in pediatrics; stem cell sources and related technical choices; stem cell donors; scheduling transplantations; diseases and chemotherapy protocols that require stem cell transplantation; stem cell homing; engraftment and repopulation of stem cells in bone marrow; autologous stem cell transplantation in pediatrics; allogeneic stem cell transplantation in pediatrics; and indications for autologous and allogeneic pediatric stem cell transplantation. Further, it discusses pediatric graft-versus-host disease and the pharmacist; antibacterial and antifungal prophylaxis; detailed chemotherapy, conditioning and trials for pediatric stem cell transplantation; conditioning granulocyte colony-stimulating factor (G-CSF) in pediatric stem cell transplantation; analyzing prescriptions and programming a pediatric stem cell transplantation; handling chemotherapy and adjuvant drugs for pediatric stem cell transplantation; stem cell transplantation in children up to 1 year old; and clinical pharmacy in pediatric stem cell transplantation. An easy-to-read yet comprehensive guide covering a wide range of topics essential to daily practice, the book offers an invaluable asset for pediatric hemato/ oncology pharmacists, hematologist pharmacists, clinical pharmacists, pediatric pharmacists, pharmaceutical residents and researchers alike.

Cell and Gene Therapies

Cell and Gene Therapies
  • Author : Miguel-Angel Perales,Syed A. Abutalib,Catherine Bollard
  • Publisher :
  • Release Date :2018-11-27
  • Total pages :288
  • ISBN : 3319543687
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Summary : In this book, experts in the field express their well-reasoned opinions on a range of complex, clinically relevant issues across the full spectrum of cell and gene therapies with the aim of providing trainee and practicing hematologists, including hematopoietic transplant physicians, with information that is relevant to clinical practice and ongoing research. Each chapter focuses on a particular topic, and the concise text is supported by numerous working tables, algorithms, and figures. Whenever appropriate, guidance is provided regarding the availability of potentially high-impact clinical trials. The rapid evolution of cell and gene therapies is giving rise to numerous controversies that need to be carefully addressed. In meeting this challenge, this book will appeal to all residents, fellows, and faculty members responsible for the care of hematopoietic cell transplant patients. It will also offer a robust, engaging tool to aid vital activities in the daily work of every hematology and oncology trainee.

Pulmonary Considerations in Solid Organ and Hematopoietic Stem Cell Transplantation, An Issue of Clinics in Chest Medicine, E-Book

Pulmonary Considerations in Solid Organ and Hematopoietic Stem Cell Transplantation, An Issue of Clinics in Chest Medicine, E-Book
  • Author : Vivek Ahya,Joshua Diamond
  • Publisher :
  • Release Date :2017-11-19
  • Total pages :329
  • ISBN : 0323552714
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Summary : This issue of Clinics in Chest Medicine focuses on Pulmonary Considerations in Solid Organ and Hematopoietic Stem Cell Transplantation. Editors Vivek Ahya and Joshua Diamond have assembled an expert team of authors on topics such as: Overview of HSCT Transplantation and future directions in treatment of hematologic malignancies; Early Pulmonary complications of HSCT and Prognosis of Respiratory FailureLate Pulmonary complications of HSCT; Overview of Lung Transplantation, Heart-lung transplantation, Lung-Liver transplantation and combined HSCT and lung transplantation; Primary graft dysfunction after Lung Transplantation; Extracorporeal life support (ECLS) in lung transplantation; Evaluation and Management of the potential lung donor (including EVLP); Acute rejection & antibody mediated rejection in lung transplantation; Chronic lung allograft dysfunction (CLAD); Airway complications in lung transplantation; PTLD in solid organ and HSCT transplantation; Respiratory Bacterial and Mycobacterial Infections in solid organ transplantation and HSCT; Respiratory Viral infections in solid organ transplantation and HSCT; Respiratory Fungal infections in solid organ and hematopoietic stem cell transplantation; Non-infectious pulmonary complications of Liver, Heart and Kidney Transplantation; Hepatopulmonary syndrome and portal- pulmonary hypertension in liver failure; implications for liver transplantation.

Cancer Nursing

Cancer Nursing
  • Author : Connie Henke Yarbro,Michelle Goodman,Margaret Hansen Frogge
  • Publisher :
  • Release Date :2005
  • Total pages :1879
  • ISBN : 9780763747206
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Summary : Rapid changes in oncology necessitate a comprehensive, up-to-date reference for oncology nurses. For seventeen years, best-selling Cancer Nursing: Principles and Practice has filled this need, supplying oncology nurses with cutting-edge, current information. Now, in its Sixth Edition, Cancer Nursing reflects the constantly shifting progress in the science of oncology, as well as emerging new therapies, new treatment modalities, the latest results from clinical trials, updates on new chemotherapeutic agents and targeted therapies, and new perspectives on supportive care.

Blood and Marrow Stem Cell Transplantation

Blood and Marrow Stem Cell Transplantation
  • Author : Marie Bakitas Whedon,Debra Wujcik
  • Publisher :
  • Release Date :1997
  • Total pages :587
  • ISBN : 9780763703561
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Summary : Nursing

Mosby's Oncology Nursing Advisor E-Book

Mosby's Oncology Nursing Advisor E-Book
  • Author : Susan Newton,Margie Hickey,Jeannine Brant
  • Publisher :
  • Release Date :2016-09-10
  • Total pages :528
  • ISBN : 0323449115
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Summary : Get quick access to the most important information surrounding cancer and oncology nursing care with Mosby’s Oncology Nursing Advisor, 2nd Edition. Covering everything from the various types of cancer and cancer treatment options to patient education and nursing best-practices, this indispensable nursing guide is like getting seven books in one! Plus, its user-friendly layout and straightforward coverage make it ideal for use in any clinical setting. With 17 new chapters, updated evidence-based content throughout, and proven patient teaching handouts, this new edition offers the authoritative guidance you need to provide the best possible oncology nursing care. Detailed descriptions of over 50 major cancer types provide essential information on incidence, etiology and risk factors, signs and symptoms, diagnostic workup, histology, staging, treatment, prognosis, and prevention. Coverage of cancer management principles outlines a wide range of treatment and pharmacologic modalities, including surgery, chemotherapy, radiation therapy, hormonal therapy, immunotherapy, and complementary and alternative therapies. Symptom management guidelines offer in-depth coverage of pathophysiology, signs and symptoms, assessment tools, lab and diagnostic tests, differential diagnoses, interventions, patient education, follow up care, and resources for over 30 common symptoms associated with cancer and cancer treatments. Essential information on many oncologic emergencies and emergent issues prepares readers to respond quickly to structural, metabolic, and hematologic emergencies. Section on palliative care and end-of-life issues offers helpful guidelines for dealing with topics related to survivorship, palliative care, the final hours of the cancer patient, and loss, grief, and bereavement. NEW! Updated evidence-based content reflects the latest national and international quality standards regarding various cancer types, major drug and non-drug treatments, treatment protocols, and approaches to symptom management. NEW! Nursing Practice Considerations section incorporates information on communication, cultural considerations, ethical considerations, safe and quality care, evidence-based practice, patient navigation, and patient education. NEW! 17 new chapters cover topics including myelofibrosis, neuroendocrine cancers, tumor treating fields, oral adherence, clinical trials, epistaxis, hypersensitivity reactions, hypertension, hyperglycemia, nail changes, ocular and visual changes, rashes, survivorship, quality and safety, evidence-based practice, nurse navigation, and patient education. NEW! Expanded content on patient education keeps readers on top of best practices in this critical area. NEW! High-quality electronic patient teaching handouts are evidence-based and have been vetted by practicing nurses.